A hierarchy of timescales explains distinct effects of local inhibition of primary visual cortex and frontal eye fields

L Cocchi; MV Sale; LL Gollo; PT Bell; VT Nguyen; A Zalesky; M Breakspear; JB Mattingley

Journal article

A hierarchy of timescales explains distinct effects of local inhibition of primary visual cortex and frontal eye fields

L Cocchi, MV Sale, LL Gollo, PT Bell, VT Nguyen, A Zalesky, M Breakspear, JB Mattingley

Elife | ELIFE SCIENCES PUBLICATIONS LTD | Published : 2016

DOI: 10.7554/eLife.15252

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Abstract

Within the primate visual system, areas at lower levels of the cortical hierarchy process basic visual features, whereas those at higher levels, such as the frontal eye fields (FEF), are thought to modulate sensory processes via feedback connections. Despite these functional exchanges during perception, there is little shared activity between early and late visual regions at rest. How interactions emerge between regions encompassing distinct levels of the visual hierarchy remains unknown. Here we combined neuroimaging, non-invasive cortical stimulation and computational modelling to characterize changes in functional interactions across widespread neural networks before and after local inhib..

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University of Melbourne Researchers

Andrew Zalesky Author

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Grants

Awarded by National Health and Medical Research Council

Awarded by ECR grant from the University of Queensland

Awarded by Australian Research Council

Funding Acknowledgements

National Health and Medical Research Council APP1099082 Luca Cocchi Martin V Sale Jason B Mattingley Andrew ZaleskyECR grant from the University of Queensland ECR125 Luca CocchiNational Health and Medical Research Council APP1028210 Martin V SaleNational Health and Medical Research Council APP1110975 Leonardo L GolloNational Health and Medical Research Council APP1047648 Andrew ZaleskyAustralian Research Council CE140100007 Michael Breakspear Jason B MattingleyAustralian Research Council FL110100103 Jason B MattingleyThe funders had no role in study design, data collection and interpretation, or the decision to submit the work for publication.